Dr. Call is a nationally recognized, award-winning scholar who has an active research program in food and water-borne diseases and salmonid aquaculture.
His research is focused on:
- Mechanisms that lead to the emergence, amplification, persistence and dissemination of antibiotic resistance in food animal production systems (E. coli and Salmonella).
- Development of vaccine, microcin and probiotic tools to combat zoonotic and animal pathogens independent of antibiotics.
- Potential of hyperosmotic agents and other strategies as tools for preventing or treating wound and other biofilms (MRSA,Acinetobacter, Campylobacter).
- The development of algorithms to rapidly genotype and fingerprint bacteria using next-generation sequencing. He applies these tools to improve clinical outcomes and to study the molecular epidemiology of bacterial pathogens.
- Contact-dependent regulation of type III secretion systems in the food-borne pathogen Vibrio parahaemolyticus.
Dr. Call has been recognized for his scholarly achievements with honors that include the American Society for Investigative Pathology Merit Award, an EPA Science to Achieve Results Fellowship, and he was the inaugural Caroline Engle Distinguished Professor in Research on Infectious Diseases from 2009 to 2012.
Dr. Call is a professor of molecular epidemiology in the Paul G. Allen School for Global Animal Health conducting multi-disciplinary research in Tanzania concerning the ecology of antibiotic resistance; additional collaborative research is underway in Kenya and Nigeria. Other funded work concerns enterohemorrhagic E. coli, wound-biofilm interactions, and antibiotic resistance genotyping. He also researches the role that excreted antibiotic residue plays in the amplification and persistence of antibiotic-resistant bacteria on farms.